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Recent Research on Bulimia Nervosa By James E. Mitchell, MD and Kristine J. Steffen, PharmD In thinking about areas on which to focus this review, the possibilities seemed endless. Therefore, we have chosen a few representative areas but realize we do so at the expense of much very important work. Two issues of ongoing concern are the health problems of patients with eating disorders and their use of health services. Spoor and colleagues (2007), using community-recruited samples, found that the total number of occurrences of binge eating and compensatory behaviors, or simply compensatory behaviors occurring twice a week, resulted in greater self-reported health-care utilization using items from the Health Survey Utilization Scale that assessed both mental and physical health care utilization. Mond and colleagues (2007), again using a community sample, found that women with bulimic-type eating disorders rarely received treatment for an eating disorder but often received treatment for other mental health problems and/or for weight loss. Ecological momentary assessment (EMA) has emerged as a helpful tool, as shown in several studies. (EMA allows patients to record symptoms, affect, and behavior close in time to the experience. Using diaries, PDAs or cell phones, many events and experiences can be recorded by patients near the time they occur.) Negative affect has received increasing attention as a precipitant of binge eating in patients with bulimia nervosa (BN). Hilbert and TuschenCaffier (2007), using EMA, found that a patient’s mood was more negative beforebinge eating, which was followed by a further deterioration of mood. Also using EMA, Smyth and colleagues (2007) showed that days characterized by binge eating or vomiting were also marked by higher negative affect and higher anger/ hostility and more self-reported stress. Within-day recordings showed that decreasing positive affect and increasing negative affect and anger/hostility reliably preceded BN events such as binge eating and purging. Engelberg and colleagues (2007), also using EMA, also found that negative affect as well as dissociation was elevated prior to binge eating episodes. Treatment update Vanderlindin et al. (2007) surveyed a large sample of eating disorder patients to find which elements in their treatment they thought were most helpful in their recovery. “Improving self-esteem,” “improving body experience,” and “learning problem-solving skills” were all considered core elements that helped recovery. All of these were very similar to the items endorsed by therapists as the most important therapeutic agents. Wilson (2007) reviewed psychological treatments for eating disorders, and concluded that manual-based CBT is presently the most effective treatment for BN. He also discussed various strategies for improving results obtained with CBT, including combining CBT with antidepressant medication, integrating CBT with alternative psychological therapies, and expanding the scope and flexibility of manual-based CBT. In what is the first randomized controlled trial of the treatment of adolescents with BN, le Grange and colleagues (2007) compared family-based treatment to supportive psychotherapy. Forty-one patients were randomized to family-based treatment and 39 to supportive psychotherapy. The familybased treatment showed a clinical and statistical advantage over supportive psychotherapy post-treatment and at a six-month follow-up. Long-term outcome Comorbidity About the Authors Dr. Steffen is a Research Scientist at the Neuropsychiatric Research Institute. References Fichter MM, Quadflieg N. Long-term stability of eating disorder diagnoses. Int J Eat Disord. 2007; Nov; 40 Suppl:S61-6. Grilo CM, Pagano ME, Skodol AE, et al. Natural course of bulimia nervosa and of eating disorder not otherwise specified: 5-year prospective study of remissions, relapses, and the effects of personality disorder. J Clin Psychiatry. 2007; 68:738. Hilbert A, Tuschen-Caffier B. Maintenance of binge eating through negative mood: a naturalistic comparison of binge eating disorder and bulimia nervosa. Int J Eat Disord. 2007; 40:521. leGrange D, Crosby RD, Rathous PH, Leventhal BL. A randomized controlled comparison of family-based treatment and supportive psychotherapy for adolescent bulimia nervosa. Arch Gen Psychiatry. 2007; 64:1049. Mond JM, Hay PJ, Rodgers B, Owen C. Health service utilization for eating disorders: findings from a community-based study. Int J Eat Disord. 2007;40:399. Shapiro JR, Berkman ND, Brownley KA, et al. Bulimia nervosa treatment: a systematic review of randomized controlled trials. Int J Eat Disord. 2007; 40:321. Smyth JM, Wonderlich SA, Heron KE, et al. Daily and momentary mood and stress are associated with binge eating and vomiting in bulimia nervosa patients in the natural environment. J Consult Clin Psychol. 2007; 75:629. Spoor STP, Stice E, Burton E, Bohon C. Additional Resources: |



